Narrative Review: Continuous Glucose Monitoring (CGM) in Older Adults with Diabetes

Continuous glucose monitoring (CGM) has revolutionised diabetes care, with proven effect on glycaemic control, adverse diabetic events (such as hypoglycaemia and diabetic ketoacidosis) and hospitalisations in the general population. However, the evidence for CGM in older people is less robust.

We conducted a narrative review of trials reporting data comparing standard blood glucose monitoring (SBGM) and CGM in adults over 65 with type 1 or type 2 diabetes who were treated with insulin published between 1999 and 2024.

Seventeen studies were identified, including eight retrospective cohort studies and five randomised controlled trials (RCTs). Sixteen of the 17 papers were based in Europe or North America. The studies were highly heterogeneous; however, they provided clear evidence supporting the use of CGM in reducing hypoglycemia in older adults, with potential benefits for overall wellbeing and quality of life..

Current approaches to diabetes care in older adults may over-rely on HbA1c (haemoglobin A1c) as a measurement of control given accuracy may be reduced in older adults and propensity for hypoglycaemia. Although goals should be personalised, avoidance of hypoglycaemia is a key goal for many older people with diabetes. There is good evidence that CGM can improve time-in-range and reduce hypoglycaemia and glucose variability in older adults. CGM should be considered for older adults as a means of reducing hypoglycaemia and associated potential harm.