Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

1.5K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Calculating IOL power - principles, development and current challenges].

Die Ophthalmologie·2026
Same author

Difference in Ocular Perfusion Drop After Intravitreal Aflibercept in Patients with Neovascular AMD and Diabetic Macular Edema.

Current eye research·2026
Same author

Structural anterior segment OCT biomarkers do not predict secondary intervention after Preserflo MicroShunt implantation.

Frontiers in medicine·2026
Same author

Predicting Postoperative Anterior Chamber Depth, Intraocular Lens Tilt, and Decentration Using an Internally Validated Machine Learning Model.

Ophthalmology and therapy·2026
Same author

Preoperative Surgical Site Vessel Density Is Predictive for Secondary Intervention after Preserflo Microshunt Implantation.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Erratum to: Clinical feasibility of the ESCRS IOL power calculator.

Journal of cataract and refractive surgery·2026

Related Experiment Video

Updated: May 13, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

2.8K

Quantification of physiological crystalline Lens decentration using swept source OCT.

Peter Laubichler1,2, Haidar Khalil1,2, Theresa Höftberger1,2

  • 1Ophthalmology and Optometry, Kepler Universitatsklinikum GmbH, Linz, Austria.

European Journal of Ophthalmology
|April 16, 2025
PubMed
Summary

Crystalline lens decentration in adults averaged 0.212 mm, with less than 0.3 mm considered physiological. Understanding lens position and biometric factors can improve surgical outcomes and patient satisfaction.

Keywords:
BiometryCATARACTIOL calculation for primary IOLLENSaxial lengthbiochemistry/Physiologyepidemiology

More Related Videos

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

9.2K
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.5K

Related Experiment Videos

Last Updated: May 13, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

2.8K
Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

9.2K
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.5K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Data Science

Background:

  • Crystalline lens decentration can impact visual quality and refractive outcomes after cataract surgery.
  • Accurate quantification of lens decentration is crucial for personalized ophthalmic procedures.

Purpose of the Study:

  • To quantify crystalline lens decentration in a large Austrian adult cohort (cataractous and non-cataractous).
  • To predict lens decentration using preoperative biometric parameters.
  • To establish a physiological threshold for lens decentration.

Main Methods:

  • Retrospective analysis of preoperative data from 4731 eyes (2531 patients).
  • Measurements included optical biometry and anterior segment optical coherence tomography.
  • A random forest machine learning algorithm was used for decentration prediction.

Main Results:

  • The overall mean lens decentration was 0.212 mm.
  • 5.3% of patients exhibited decentration exceeding 0.4 mm.
  • Low but significant correlations were found between decentration and tilt, corneal width, lens diameter, and anterior chamber depth.

Conclusions:

  • A lens decentration amount less than 0.3 mm is considered physiological.
  • Preoperative assessment of physiological decentration aids in improving postoperative refractive outcomes.
  • This analysis supports better patient satisfaction, particularly with premium intraocular lens selection.