Related Experiment Video
Updated: May 13, 2025
04:38
Subcostal Specimen Removal in Completely Portal Robotic Lobectomy
Published on: April 19, 2024
238
Segmentectomy versus lobectomy for intersegmental small-sized non-small cell lung cancer.
Shengzhe Zhou1, Shusheng Zhu2, Zhihua Li1
1Department of Thoracic Surgery, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Summary
Intersegmental non-small cell lung cancer (NSCLC) has similar outcomes to non-intersegmental NSCLC, despite higher lymph node metastasis. Segmentectomy offers comparable long-term survival to lobectomy for select intersegmental NSCLC cases.
Area of Science:
- Thoracic surgery
- Surgical oncology
- Pulmonary medicine
Background:
- Intersegmental non-small cell lung cancer (NSCLC) involves lesions across two or more lung segments.
- Understanding the characteristics and prognosis of intersegmental NSCLC is crucial for surgical decision-making.
Purpose of the Study:
- To characterize intersegmental NSCLC.
- To compare the prognostic outcomes of segmentectomy versus lobectomy for intersegmental NSCLC.
Main Methods:
- Retrospective analysis of 1702 patients with small-sized NSCLC (2012-2020).
- Intersegmental nodules identified using 3D computed tomographic bronchography and angiography.
- Prognostic analyses employed log-rank tests and Cox regression.
Main Results:
- Intersegmental nodules (25%) were linked to larger tumor size and higher lymph node metastasis rates (5.4% vs. 2.1%).
- Segmentectomy for intersegmental nodules involved longer operative times and larger resected lung volumes.
- Propensity score-matched analysis showed segmentectomy (n=75) yielded comparable 5-year overall and disease-free survival to lobectomy (n=75) for intersegmental NSCLC.
Conclusions:
- Intersegmental NSCLC exhibits a similar prognosis to non-intersegmental NSCLC, with a notable increase in lymph node metastasis.
- Segmentectomy is a viable surgical option for selected intersegmental NSCLC cases, achieving long-term results comparable to lobectomy.
