Myopia progression in children with Stickler syndrome: a longitudinal cohort study

Studies of myopia progression in congenital myopia, as seen in genetically confirmed Stickler syndrome, are scarce. Stickler syndrome represents the most common cause of rhegmatogenous retinal detachment in children. The purpose of this retrospective study was to determine the rate of myopia progression in a cohort of 40 children (75 eyes) with type 1 Stickler syndrome (COL2A1 mutation) and 5 children (10 eyes) with type 2 Stickler syndrome (COL11A1 mutation). In this cohort, the median rate of progression was -0.08 D per year for those with type 1 Stickler syndrome and -0.12 D per year for those with type 2 Stickler syndrome, indicating minimal myopia progression in these children.