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Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

77
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
77
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

36
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
36
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

541
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
541
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

967
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
967
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

42
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
42
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

19
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
19

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Related Experiment Video

Updated: May 11, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

608

Eosinophilic Esophageal Myositis.

Ajay Pranami1, Amol Dahale1, Abhijeet Karad1

  • 1Department of Medical Gastroenterology, Dr. D Y Patil Vidyapeeth, Dr. D Y Patil Medical College, Hospital and Research Centre, Pune, India.

ACG Case Reports Journal
|April 17, 2025
PubMed
Summary

Eosinophilic esophageal myositis (EoEM) is a rare esophageal disorder. This study highlights endoscopic ultrasound for diagnosing EoEM and its successful treatment with steroids.

Keywords:
dysphagiaendoscopic ultrasoundeosinophilic esophageal myositiseosinophilic esophagitiseosinophilic gastrointestinal diseasesjackhammer esophagusnutcracker esophagusper oral endoscopic myotomy

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Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Eosinophilic esophageal myositis (EoEM) is a rare condition characterized by eosinophilic infiltration of the muscularis propria of the esophagus.
  • It presents with symptoms like chest pain, dysphagia, and food impaction, often mimicking eosinophilic esophagitis, complicating diagnosis.

Observation:

  • A 73-year-old male patient presented with symptoms suggestive of esophageal pathology.
  • Endoscopic ultrasound (EUS) was utilized to assess the esophageal wall layers and guide biopsy.

Findings:

  • EUS confirmed EoEM by visualizing involvement of the muscularis propria.
  • The patient received steroid therapy, leading to a successful clinical outcome.

Implications:

  • Endoscopic ultrasound is a valuable tool for diagnosing EoEM, differentiating it from eosinophilic esophagitis.
  • Early diagnosis and medical management, such as with steroids, are crucial for treating EoEM and preventing complications.