Plummer-Vinson Syndrome With Coexistent Thyro-Cardiac Disease and Acute Decompensated Heart Failure: A Case Report

Plummer-Vinson Syndrome (PVS) is a rare disorder characterized by the triad of dysphagia, iron-deficiency anemia, and esophageal webs. Limited data on its prevalence exist, with most information derived from case reports. We present the case of a 60-year-old woman with a 6-month history of a progressively enlarging anterior neck mass and worsening symptoms of heart failure, heat intolerance, and dysphagia. Diagnostic evaluation revealed a multinodular goiter, microcytic hypochromic anemia, hyperthyroidism, hypokalemia, and esophageal webs. She was diagnosed with PVS in conjunction with thyro-cardiac disease and acute decompensated heart failure. Treatment included iron supplementation, pneumatic dilation, and management of her thyroid and cardiac conditions, resulting in significant clinical improvement. This case demonstrates the importance of early recognition and treatment of PVS to prevent complications and reduce morbidity.