Paracentral Acute Middle Maculopathy in a Pregnant Woman on Supplemental Hormones for Invitro-Fertilization

This case study examines the rare occurrence of paracentral acute middle maculopathy (PAMM) in a first-trimester pregnant patient, highlighting the importance of promptly addressing acute neurological symptoms in expectant mothers. PAMM, a retinal vascular disorder causing ischemic damage to the middle retinal layers, is sparsely documented in literature. The patient, a 31-year-old primigravida with migraines and elevated anti-nucleic acid titer, presented with sudden painless monocular vision loss. Initially suspected as a migraine aura, persistent symptoms led to a comprehensive evaluation. Imaging and consultations confirmed PAMM, likely due to retinal microvascular occlusion exacerbated by her hypercoagulable state and inflammation. This case underscores the need for thorough differential diagnosis and interdisciplinary collaboration in managing pregnant patients with acute neurological symptoms, ensuring optimal outcomes for mother and fetus.