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Published on: February 27, 2018
The establishment of specified-pathogen-free marmosets, Callithrix jacchus
Laboratory Animals
|January 1, 1977
Summary
This study details the successful establishment of three specified-pathogen-free marmosets (Callithrix jacchus) using advanced hysterotomy and hand-rearing techniques. These methods ensured the health and viability of the new primate colony.
Area of Science:
- Primate research
- Animal husbandry
- Pathogen-free animal models
Background:
- Conventional breeding colonies can harbor pathogens, impacting research integrity.
- Need for healthy, disease-free animal models in biomedical research.
- Marmosets (Callithrix jacchus) are valuable non-human primates for scientific studies.
Purpose of the Study:
- To describe the establishment of specified-pathogen-free (SPF) marmosets.
- To detail the techniques used for creating a disease-free primate colony.
- To provide a historical account of SPF marmoset development.
Main Methods:
- Hysterotomy procedure for sterile delivery of infant marmosets.
- Hand-rearing techniques for neonatal primate care.
- Establishment of a conventional breeding colony for animal derivation.
Main Results:
- Successfully established three specified-pathogen-free marmosets (Callithrix jacchus).
- Detailed description of the hysterotomy and hand-rearing processes.
- Provided a historical record of SPF marmoset establishment from May 1969 to January 1973.
Conclusions:
- Hysterotomy and hand-rearing are effective methods for producing SPF marmosets.
- The establishment of SPF colonies is crucial for reliable primate research.
- This work contributes to the foundation of disease-free marmoset breeding programs.
