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Related Concept Videos

Photoluminescence: Applications01:14

Photoluminescence: Applications

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Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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Updated: May 20, 2025

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Antenna effect-modulated luminescent lanthanide complexes for biological sensing.

Lingyan Gui1, Rongxian Huang1, Huichun Liang1

  • 1Department of Laboratory Medicine, The Affiliated Qingyuan Hospital (Qingyuan People's Hospital), Guangzhou Medical University, Qingyuan 511518, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|April 19, 2025
PubMed
Summary

The antenna effect significantly enhances luminescent lanthanide complexes (LLCs), improving their optical properties for advanced biosensing in food safety, environmental monitoring, and clinical diagnosis.

Keywords:
Antenna effectElectrochemiluminescenceFluorescenceLuminescent lanthanide complexesSensors

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Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Biochemistry

Background:

  • Luminescent lanthanide complexes (LLCs) have advanced optical properties.
  • The antenna effect significantly improves LLC optical characteristics, including luminescence lifetime and photostability.
  • LLCs are increasingly utilized as biosensors across various fields.

Purpose of the Study:

  • To review the design principles of antenna effect-modulated LLC sensors.
  • To classify antenna ligands used in LLCs.
  • To explore recent biological sensing applications of LLCs.

Main Methods:

  • Systematic review of LLC sensor design and antenna effect principles.
  • Detailed classification of antenna ligands.
  • Analysis of LLC applications in fluorescence and electrochemiluminescence sensors over the past three years.

Main Results:

  • Antenna effect modulation leads to enhanced LLC optical properties like long luminescence lifetimes and high photostability.
  • LLCs demonstrate broad applicability in biosensing for food safety, environmental monitoring, clinical diagnosis, and drug analysis.
  • Recent advancements highlight LLCs' roles in both fluorescence and electrochemiluminescence sensing platforms.

Conclusions:

  • Antenna effect-modulated LLCs offer superior performance for biosensing applications.
  • Further research into challenges and opportunities will drive future advancements in LLC-based sensing.
  • LLCs are poised for continued growth in sensitive and selective biological detection.