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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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[Secondary thyroid lymphoma: a misleading pathology].

María José Vallejo Herrera1, Verónica Vallejo Herrera2

  • 1Servicio de Endocrinología, Hospital Regional de Málaga, Málaga, Barcelona, España; Medicina Interna, Hospital Regional de Málaga, Málaga, Barcelona, España.

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Summary

Secondary thyroid lymphoma is rare and poses diagnostic challenges. This case highlights the importance of anatomopathological confirmation for accurate diagnosis and treatment of thyroid gland involvement.

Keywords:
AdenopathiesAdenopatíasCarcinomaLinfomaLymphomaNoduleNóduloThyroidTiroides

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Area of Science:

  • Oncology
  • Endocrinology
  • Pathology

Background:

  • Malignant thyroid lesions are common, typically of follicular origin.
  • Thyroid lymphoma, both primary and secondary, is an exceptionally rare condition.
  • Secondary thyroid lymphoma presents diagnostic difficulties, often mimicking thyroid carcinoma.

Purpose of the Study:

  • To present a case of secondary thyroid lymphoma with an initially erroneous diagnosis.
  • To emphasize the critical role of anatomopathological study in diagnosing rare thyroid conditions.
  • To illustrate the successful resolution of misdiagnosed secondary thyroid lymphoma.

Main Methods:

  • Case report presentation.
  • Review of diagnostic challenges in secondary thyroid lymphoma.
  • Highlighting the definitive role of anatomopathological confirmation.

Main Results:

  • A patient presented with secondary lymphoma involving the thyroid gland.
  • The initial diagnosis was incorrect, leading to diagnostic challenges.
  • Anatomopathological confirmation led to the correct diagnosis and resolution.

Conclusions:

  • Secondary thyroid lymphoma requires careful differential diagnosis.
  • Anatomopathological examination is essential for accurate diagnosis of thyroid lymphoma.
  • Timely and accurate diagnosis is crucial for effective management of thyroid gland malignancies.