Association Between Psychiatric Illness and Short-Term Outcomes Among Patients With Hepatobiliary and Pancreatic...

The association between psychiatric illness (PI) and outcomes after hepatobiliary and pancreatic (HPB) surgery remains unknown. Our study aimed to assess the association between psychiatric diseases and outcomes after surgery for malignant HPB diseases.

We performed a retrospective review of the 2016-2019 National Inpatient Sample (NIS) of patients undergoing HPB surgery. Patients were categorized based on the history of PI and then were matched using coarsened exact matching to patients without any PI. Outcome measures were mortality, hospital cost, and discharge disposition.

A total of 11,255 patients underwent HPB surgery with a history of PI. There was no difference in mortality (0.6% versus 1.3%; odds ratio: 0.44; 95% confidence interval: 0.14-1.44; P = 0.18) or hospital cost ($117K ± $72K versus $110K ± $71.2 K; P = 0.07) between the two groups after matching. Health care use, including rehabilitation or nursing home admissions, was higher in patients with a history of psychiatric disorders (11.6% versus 8.8%; 95% confidence interval: 1.16-1.59; odds ratio: 1.36; P < 0.05).

The study found no difference in clinical outcomes among patients with PI. We found an increased incidence of discharge to a rehabilitation facility or nursing facility in patients with psychiatric diseases, which highlights the need for more social support.