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Updated: Apr 12, 2026

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
Published on: January 29, 2011
The implementation of indirect calorimetry for patients with acute respiratory failure: Invited commentary on
Ashlee Roffe1, Michelle L Schneider2, Michelle Brown3
1Nutrition and Community Health, Endeavor Health Swedish Hospital, Chicago, Illinois, USA.
Abstract:
Respiratory failure is a life-threatening condition that occurs when the lungs are unable to deliver adequate oxygen to the blood or remove carbon dioxide from the body. Patients with respiratory failure often have difficulty maintaining oral nutrition intake because of associated breathlessness and are at increased risk of malnutrition, given both their metabolic response to stress and their dependence on nutrition support. Predictive equations assist clinicians in determining specific energy (caloric) needs for patients with respiratory failure; however, they are inaccurate, complex, and difficult to calculate. Recent technological advances have allowed for commercially available bedside measurement of energy needs using indirect calorimetry. The purpose of this review is to describe how indirect calorimetry (IC) can be used to influence clinical decision-making and nutrition care for patients with respiratory failure who are mechanically ventilated. We provide examples of how IC is utilized in a large tertiary care hospital as well as a small community hospital and strategies for successful adoption of IC.
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