Tetrafluoropyridine Regulated Site-Selective Cycloaddition of Diazoacetates with 1,4-Unsymmetrical [60]Fullerene
Sheng-Hu Yuan1, Meng-Ran Li1, Zheng-Chun Yin2
1Department of Chemistry, College of Chemistry & Chemical Engineering, Anhui University, Hefei, Anhui 230601, China.
Abstract:
Site-selective multiple addition reactions of fullerenes hold great promise for generating new nanocarbons with diverse material and biological applications. However, there are a lack of strategies for achieving site selectivity in a stepwise manner within this field. In this study, we discovered that tetrafluoropyridine-modified unsymmetrical 1,4-C60 adducts can undergo highly site-selective cycloadditions with diazoacetates. This finding suggests that leveraging the 1,4-unsymmetric bifunctional group effect can be an effective strategy for controlling the regioselectivity for further reactions of 1,4-(organo)[60]fullerene.
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