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Updated: May 10, 2025

Engineering a Bilayered Hydrogel to Control ASC Differentiation
Published on: May 25, 2012
Advancements in Biomaterials for Stem Cell Differentiation
Mingchen Shao1, Mohamad Rahmdel2, Sepideh Karkon Shayan3
1Department of Cardiovascular Surgery, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991, Moscow, Russian Federation.
Abstract:
The field of regenerative medicine has witnessed significant advancements in recent years, particularly in the application of biomaterials to enhance stem cell differentiation. Biomaterials serve as scaffolds that can support cellular functions and influence the fate of stem cells through biochemical and physical cues. This paper reviews recent advancements in biomaterials designed for stem cell differentiation, focusing on their composition, properties, and applications in tissue engineering. We explore various types of biomaterials, including natural polymers, synthetic polymers, hydrogels, and nanomaterials, and discuss how they can be tailored to create microenvironments that promote specific differentiation pathways. Additionally, we highlight the challenges and future directions in this rapidly evolving field.
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