Rare angiofibrolipoma of the oral cavity: a case report

Angiofibrolipomas are one of the rarest variants of lipoma, a benign mesenchymal tumor composed of adipose tissue. Histologic examination of angiofibrolipomas reveals mature adipocytes, vascular tissue, and fibrous connective tissue. This case report describes an angiofibrolipoma in the oral cavity of a 40-year-old woman. A soft, painless, pedunculated mass was attached to the distolingual gingiva in the region of the mandibular third molar. The provisional diagnosis was pyogenic granuloma. The mass was excised using electrocautery, and the tissue was submitted for histologic examination. Histologic staining revealed mature adipose tissue, fibrous tissue, and numerous small blood vessels, consistent with a diagnosis of angiofibrolipoma. Further immunohistochemical analysis with CD34 biomarker was performed to rule out spindle cell carcinoma. At the 1-year follow-up examination, no recurrence was found. However, due to the rarity of these tumors, more data are needed to determine their recurrence rate.