Related Experiment Video
Updated: Jul 17, 2026

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
Published on: February 27, 2018
Decreased Revision Risk With Cementless Collared Metadiaphyseal-Filling Stems Compared to Cemented Fixation in
Mackenzie Kelly1, Ryland Kagan1, Isabella Zaniletti2
1Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, Oregon.
Background:
Compared to other cementless designs, collared metadiaphyseal-filling femoral stems are associated with a lower risk of revision and periprosthetic femoral fracture after total hip arthroplasty (THA) in patients ≥ 65 years. However, it is unclear how these designs compare to cemented femoral stems. We utilized the American Joint Replacement Registry to examine the risk of revision comparing cementless collared metadiaphyseal-filling versus cemented femoral stem designs.
Methods:
Data from 2012 to 2021 was analyzed in patients ≥ 65 years, linked to Centers for Medicare and Medicaid data. We identified 79,022 primary THAs, stratified into two groups: cementless collared metadiaphyseal-filling stems (n = 61,854) and cemented fixation (n = 17,168). Inverse-probability-of-treatment-weighting cause-specific Cox proportional hazard models were used to evaluate the risks of all-cause revision and revision for periprosthetic femoral fracture, aseptic loosening, dislocation, and infection.
Results:
Compared to cemented stems, cementless collared metadiaphyseal-filling stems showed a lower risk of all-cause revision (hazard ratio [HR] 0.46, 95% confidence interval [CI] 0.38 to 0.56, P < 0.001), aseptic loosening (HR 0.35, CI 0.22 to 0.57, P < 0.001), dislocation (HR 0.39, CI 0.26 to 0.58, P < 0.001), and infection (HR 0.53, CI 0.36 to 0.78, P = 0.001). There was no difference in periprosthetic femoral fracture risk (HR 0.80, CI 0.45 to 1.42, P = 0.44).
Conclusions:
In this cohort of patients undergoing primary THA, cementless collared metadiaphyseal-filling stems were associated with decreased risk of all-cause revision, revision for aseptic loosening, dislocation, and infection, but there was no difference in periprosthetic femoral fracture risk compared to cemented stems. Further study of cementless collared metadiaphyseal-filling designs compared to cemented fixation is warranted as there may be benefits of decreased revision risk with cementless fixation.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Pharmacodynamics in Geriatric Patients: Effects of Age
Aneurysm III: Interprofessional Care

