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Prevalence of Common Contact Allergens in Topical Diaper Preparations for Infants

Jessica Johnson1, Catalina Matiz2, Shehla Admani3

  • 1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA.

Pediatric Dermatology
|April 23, 2025
PubMed

Insights

Persistent perineal dermatitis may stem from allergic contact dermatitis. Many popular diaper creams contain potential allergens, highlighting the need for careful product selection to protect infant skin.

Area of Science:

  • Dermatology
  • Allergology
  • Pediatrics

Background:

  • Persistent perineal dermatitis (PD) in infants often necessitates considering allergic contact dermatitis.
  • Identifying and avoiding common allergens in topical diaper preparations is crucial for managing PD.

Purpose of the Study:

  • To analyze the allergen content of best-selling diaper preparations.
  • To identify products free from common allergens listed in the 2018 Pediatric Baseline Patch Test Series and North American Contact Dermatitis Group-70.

Main Methods:

  • A review of best-selling diaper preparations available online was conducted.
  • Products were assessed for the presence of allergens based on established patch test series.

Main Results:

  • A significant majority of reviewed diaper preparations (84%) contained one or more potential allergens.
  • Specific products identified as allergen-free according to the tested criteria are listed.

Conclusions:

  • Many over-the-counter diaper creams contain ingredients that may trigger allergic contact dermatitis.
  • Parents and caregivers should be aware of potential allergens in diaper products to prevent or manage persistent perineal dermatitis.

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