The Pathogenic Potential of Slackia exigua: A Case Study of Bacteremia in a Patient With Oral Infection

Slackia exigua is an anaerobic, Gram-positive, nonspore-forming bacterium that is typically part of the normal oral microbiota. It is generally considered biochemically inert and is often dismissed as a nonpathogenic contaminant in clinical cultures, particularly in respiratory samples. However, in this case study, we report a rare instance of S. exigua bacteremia in a patient with multiple medical comorbidities who was hospitalized after reporting to Emergency Department due to fatigue and right ear pain. The patient subsequently developed signs of persistent symptoms of septicemia, prompting an extensive investigation. Blood cultures identified S. exigua as the causative agent. This case underscores the importance of thorough culture workup and clinical correlation, especially in immunocompromised patients and patients with multiple medical comorbidities. Comprehensive dental care and the administration of targeted antibiotic therapy resulted in the patient's full recovery. This report highlights the potential pathogenic role of S. exigua in certain clinical scenarios and emphasizes the need for awareness of its possible implications in systemic infections.