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Updated: May 10, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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RETRACTION: Forkhead Box p3 Controls Progression of Oral Lichen Planus by Regulating MicroRNA-146a

    Journal of Cellular Biochemistry
    |April 23, 2025
    PubMed
    Abstract

    Insights

    This study investigated the role of Forkhead Box p3 in oral lichen planus. The article has been retracted due to concerns regarding image duplication and lack of author response.

    Area of Science:

    • Biochemistry
    • Immunology
    • Oral Medicine

    Background:

    • Oral lichen planus (OLP) is a chronic inflammatory condition affecting oral mucosa.
    • The role of specific transcription factors and microRNAs in OLP pathogenesis requires further elucidation.

    Purpose of the Study:

    • To investigate the role of Forkhead Box p3 (FOXP3) in the progression of oral lichen planus.
    • To determine if FOXP3 regulates microRNA-146a (miR-146a) expression in the context of OLP.

    Main Methods:

    • The study aimed to analyze FOXP3 expression and its correlation with miR-146a levels in OLP tissues.
    • Methods likely involved molecular biology techniques to assess gene and microRNA expression.

    Main Results:

    • The article reported that FOXP3 controls OLP progression by regulating miR-146a.
    • Specific findings regarding the molecular mechanisms were presented.

    Conclusions:

    • The study concluded that the FOXP3/miR-146a axis plays a significant role in OLP.
    • These findings suggested potential therapeutic targets for OLP.

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