Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Data Volume and the Need for Clinical Decision Support in Glaucoma Care.

Ophthalmology science·2026

Same author

Extraction of Glaucoma Diagnosis, Type, and Severity from Clinical Notes using Secure Cloud-based Large Language Models.

medRxiv : the preprint server for health sciences·2026

Same author

GLLaucoMed: A Secure LLM-Powered Agentic Workflow for Automated Medication Extraction from Free-Text Glaucoma Clinical Notes.

medRxiv : the preprint server for health sciences·2026

Same author

Sensorimotor Disturbances After Extended Depth of Focus Intraocular Lens Implantation.

Journal of binocular vision and ocular motility·2026

Same author

Optic Disc Fundus Images Retain Biometric Identity Signals Under Deep Learning.

Research square·2026

Same author

Development and Pilot Testing of a Mobile App Psychosocial Intervention for Psychological Distress in Individuals with Glaucoma.

medRxiv : the preprint server for health sciences·2026

Search research articles

Related Experiment Video

Updated: May 10, 2025

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

Longitudinal Simulated Driving Performance and Rates of Progressive Visual Field Loss in Glaucoma.

Davina A Malek¹, Alberto Diniz-Filho², Erwin R Boer^2,3

¹Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.

Translational Vision Science & Technology

|April 23, 2025

Summary

This summary is machine-generated.

Glaucoma patients with faster vision loss show increased reaction times in driving simulations. This indicates a higher risk of declining driving performance as their visual field worsens.

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

Related Experiment Videos

Last Updated: May 10, 2025

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

Area of Science:

Ophthalmology
Neuroscience
Human Factors Engineering

Background:

Glaucoma is a progressive optic neuropathy leading to irreversible vision loss.
Visual field (VF) defects in glaucoma can impact functional abilities, including driving.
Longitudinal studies are needed to understand the relationship between VF progression and driving performance.

Purpose of the Study:

To investigate the association between the rate of progressive visual field loss and changes in driving performance using simulation.
To quantify how declining visual sensitivity over time affects driving metrics in glaucoma patients.

Main Methods:

Ninety-five glaucoma patients underwent regular Standard Automated Perimetry (SAP) and driving simulations.
Visual field loss rates were determined by changes in mean sensitivity (MS) over time.
Driving performance was assessed via lane keeping and divided attention tasks, measuring reaction time (RT).

Main Results:

Progressive VF loss correlated with increased mean reaction times (RT) in divided attention tasks.
Faster loss of integrated binocular mean sensitivity (MS) was significantly associated with slower RT.
Worse baseline MS also predicted poorer driving performance.

Conclusions:

Accelerated visual field progression in glaucoma is linked to impaired divided attention during simulated driving.
Glaucoma patients with faster VF loss may face a greater risk of functional decline in driving ability.