Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial intelligence for food innovation.

Nature food·2026
Same author

Optimization of extraction, chemical characterization, and in vitro antioxidant and anti-inflammatory mechanisms of Corydalis yanhusuo alkaloids.

Journal of ethnopharmacology·2026
Same author

Risk factors for pulmonary tuberculosis recurrence in Henan, China, from 2014 to 2024.

Scientific reports·2026
Same author

Leaching behavior of RM-FGD based backfilling grout under cyclic-pressure and wet-dry cycles induced by underground water level fluctuation.

Environmental research·2026
Same author

5'-End Translationalization: Iterative Assembly of Leaderless Polycistronic Amplifiers for Context-Independent Expression in the Food-Grade Bacterium <i>Corynebacterium glutamicum</i>.

Journal of agricultural and food chemistry·2026
Same author

Navigating adoption barriers for microbial proteins in future food.

Nature communications·2026

Related Experiment Video

Updated: May 10, 2025

Cultivation of Green Microalgae in Bubble Column Photobioreactors and an Assay for Neutral Lipids
11:08

Cultivation of Green Microalgae in Bubble Column Photobioreactors and an Assay for Neutral Lipids

Published on: January 7, 2019

20.8K

Microalgae-based vaccines for aquaculture.

Haohong Chen1, Jianguo Jiang2, Rodrigo Ledesma-Amaro3

  • 1School of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, China; Imperial College Centre for Synthetic Biology, Imperial College London, London, SW7 2AZ, UK; Bezos Centre for Sustainable Protein, Imperial College London, London, SW7 2AZ, UK; Engineering Biology Microbial Food Hub, Imperial College London, London, SW7 2AZ, UK; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.

Trends in Biotechnology
|April 23, 2025
PubMed
Summary
This summary is machine-generated.

Microalgae-based oral vaccines enhance fish immunity and prevent disease in aquaculture. Future innovations in synthetic biology and fish immune metabolism will advance these sustainable vaccines.

Keywords:
engineering biologyfish pathogen immunitymicroalgae-based vaccinesoral vaccine deliveryrational designsynthetic biology

More Related Videos

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines
05:39

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Published on: October 30, 2018

11.9K
Microalgae Cultivation and Biomass Quantification in a Bench-Scale Photobioreactor with Corrosive Flue Gases
08:41

Microalgae Cultivation and Biomass Quantification in a Bench-Scale Photobioreactor with Corrosive Flue Gases

Published on: December 19, 2019

10.1K

Related Experiment Videos

Last Updated: May 10, 2025

Cultivation of Green Microalgae in Bubble Column Photobioreactors and an Assay for Neutral Lipids
11:08

Cultivation of Green Microalgae in Bubble Column Photobioreactors and an Assay for Neutral Lipids

Published on: January 7, 2019

20.8K
Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines
05:39

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Published on: October 30, 2018

11.9K
Microalgae Cultivation and Biomass Quantification in a Bench-Scale Photobioreactor with Corrosive Flue Gases
08:41

Microalgae Cultivation and Biomass Quantification in a Bench-Scale Photobioreactor with Corrosive Flue Gases

Published on: December 19, 2019

10.1K

Area of Science:

  • Aquaculture
  • Immunology
  • Biotechnology

Background:

  • Aquaculture faces significant challenges from fish diseases, impacting sustainability and food security.
  • Current disease control methods often rely on antibiotics, raising concerns about resistance and environmental impact.
  • Microalgae offer a promising platform for developing sustainable oral vaccines to enhance fish health.

Purpose of the Study:

  • To introduce the rational design of vaccine antigens for microalgae-based oral delivery.
  • To discuss the immune benefits and delivery mechanisms of microalgae as a vaccine vector.
  • To highlight the potential of microalgae-based vaccines in sustainable aquaculture.

Main Methods:

  • Rational design of vaccine antigens.
  • Development of microalgae as oral delivery vehicles.
  • Evaluation of immune responses and disease resistance in fish.

Main Results:

  • Demonstrated successful design of vaccine antigens suitable for microalgae presentation.
  • Showcased the potential of microalgae to deliver antigens effectively for oral vaccination.
  • Highlighted significant enhancements in fish immunity and disease resistance.

Conclusions:

  • Microalgae-based oral vaccines represent a sustainable strategy to improve fish health and reduce disease outbreaks in aquaculture.
  • Advances in synthetic biology and fish immune metabolism are key drivers for future innovation in this field.
  • This approach offers a viable alternative to traditional disease management practices, promoting a healthier aquaculture sector.