Related Experiment Video
Updated: May 10, 2025
Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
Evaluation of optical coherence tomography changes in amblyopia
Jawahar L Goyal1, Jigyasa Arora1, Abha Gahlot1
1Department of Ophthalmology, School of Medical Sciences and Research, Sharda University, Greater Noida, U.P., India.
Aim:
To study the Central Macular Thickness (CMT) and Retinal nerve fiber layer (RNFL) thickness (RNFLT) using Optical Coherence Tomography (OCT) in cases of amblyopia.
Methods And Material:
The study was conducted on 30 patients of unilateral amblyopia having vision of less than 6/12 (30 amblyopic eyes and 30 fellow eyes) and age matched 30 eyes of normal controls aged between 5-30 years. Vision, Refraction and ophthalmological examination was done. OCT changes in macula and RNFL layer were evaluated in both eyes of each patient and controls. The data was statistically analyzed using SPSS version 22.
Results:
Out of 30 patients 14 were anisomyopic and 16 were anisohyperopics. The mean central macular thickness among amblyopic eyes was significantly increased (238.77±3.64 µm) a.c.t fellow eyes (218.73±4.71µm). Average retinal nerve fibre layer thickness among amblyopic eyes was significantly increased (100.50±7.70 µm) a.c.t fellow eyes (95.67±6.38) (P<0.001).
Conclusions:
The eyes with unilateral anisometropic amblyopia were associated with higher Central Macular Thickness (CMT) and thicker global Retinal Nerve Fibre Layer (RNFL) when compared to normal fellow eyes.
More Related Videos
06:19Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
Published on: September 27, 2024
07:44In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020