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The Need for Better Validation: Evaluating Aptamer and Proximity Extension Assays for Large-Scale Clinical Proteomics

Andrew N Hoofnagle1, Michael J MacCoss2

  • 1Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.

Clinical Chemistry
|April 24, 2025
PubMed
Abstract

No abstract available in PubMed .

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
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