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Updated: May 10, 2025
Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
Published on: March 6, 2018
Modified early apical release vs. non-early apical release in holmium laser prostatic enucleation Impact on stress
Abdulghani Khogeer1, Adel Elatreisy2,3, Ahmed S Zugail1
1Department of Surgery, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
Introduction:
We aimed to compare the incidence of de novo stress urinary incontinence (SUI) of two apical release techniques for holmium laser prostatic enucleation (HoLEP): modified early apical release (EAR) and non-early apical release (non-EAR).
Methods:
We conducted a retrospective database review analyzing the records of patients who underwent HoLEP with the modified EAR and non-EAR techniques for symptomatic benign prostatic hyperplasia. The study period spanned from January 2012 to December 2021 in a single center. Patient demographics, perioperative data, and functional and technical outcomes were compared between the techniques.
Results:
The study included a total of 786 patients; 556 patients underwent the non-EAR technique (group 1), and 230 underwent the modified EAR technique (group 2). The mean enucleated prostate weight in group 1 was 68.2±45.6 g compared to 93.3±51.9 g in group 2 (p<0.001). De novo SUI within a month of surgery was reported in 34 cases (6.1%) in group 1 compared to eight cases (3.5%) in group 2. The percentage of patients with persistent SUI at one year postoperatively dropped to 2.7% and 0.9% in the non-EAR and modified EAR groups, respectively. Moreover, persistent SUI after one year from surgery was reported in 1.4 % of the non-EAR group compared to 0.44% in the modified EAR group. Multivariate regression analysis demonstrated that age >70 years (p=0.06), operative time >90 minutes (p=0.011), and the non-EAR technique (p=0.004) were significantly associated with the onset of postoperative de novo SUI.
Conclusions:
Our research indicates that both modified EAR and non-EAR techniques employed during HoLEP yield comparable efficacy and safety outcomes. Nonetheless, the modified EAR technique is associated with reduced postoperative de novo SUI.
