Study on the correlation between SINBAD system score and wound pH value in diabetic foot sarcopenia

Area of Science:

• Diabetology
• Gerontology
• Clinical Medicine

Background:

• Diabetic foot disease is a major complication of diabetes, often associated with sarcopenia, a condition characterized by loss of muscle mass and strength.
• Early diagnosis and management of sarcopenia in diabetic foot patients are crucial for improving outcomes and preventing further complications.

Purpose of the Study:

• To evaluate the diagnostic utility of the SINBAD system score and wound pH value, individually and in combination, for detecting sarcopenia in patients with diabetic foot disease.

Main Methods:

• A cross-sectional study enrolled 71 diabetic foot patients, assessing skeletal muscle index, grip strength, walking speed, SINBAD classification, and wound pH.
• Patients were categorized into non-sarcopenia, pre-sarcopenia, and sarcopenia groups based on established criteria.
• Correlation and logistic regression analyses were performed, with receiver operating characteristic (ROC) curves used to assess diagnostic value.

Main Results:

• Sarcopenia group patients exhibited longer diabetes and diabetic foot durations, lower grip strength, and reduced skeletal muscle index (SMI) compared to other groups.
• Wound pH and SINBAD scores were negatively correlated with SMI and grip strength.
• Elevated wound pH (OR=29.126) and higher SINBAD scores (OR=5.271) were significant predictors of sarcopenia.

Conclusions:

• Wound pH value and SINBAD system score are significantly associated with sarcopenia in diabetic foot patients.
• The combined assessment of wound pH and SINBAD score demonstrates high diagnostic accuracy (AUC=0.933) for diabetic foot sarcopenia.