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Plant-Based Diet and Erectile Dysfunction: A Narrative Review.

Mariana Del Carmen Fernández-Fígares Jiménez1

  • 1School of Medicine, University of Granada, Granada, Spain.

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|April 24, 2025
PubMed
Summary

A whole plant-based diet may improve erectile dysfunction (ED) by enhancing endothelial function. This diet supports nitric oxide production and reduces factors that impair blood vessel health, potentially benefiting cardiovascular health.

Keywords:
cardiometabolic risk factorscardiovascular diseasesdietaryerectile dysfunctionimpotenceplant proteinsplant-based dietvasculogenicvegan diet

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Area of Science:

  • Cardiovascular Health
  • Nutritional Science
  • Urology

Background:

  • Whole plant foods improve cardiometabolic risk factors and reduce disease risk.
  • Erectile dysfunction (ED) is a significant predictor of cardiovascular disease (CVD).
  • Endothelial dysfunction underlies arteriogenic ED.

Purpose of the Study:

  • To explore the epidemiological evidence linking whole plant-based diets to ED.
  • To investigate the biological mechanisms through which these diets may improve erectile function.

Main Methods:

  • Review of epidemiological studies on plant-based diets and ED.
  • Analysis of biological pathways affecting endothelial function and nitric oxide production.

Main Results:

  • Whole plant foods provide substrates like nitrates, L-arginine, and L-citrulline for nitric oxide (NO) synthesis.
  • This diet reduces LDL cholesterol, inflammation, and arterial stiffness, promoting NO bioavailability.
  • Improved endothelial function is linked to enhanced penile erection.

Conclusions:

  • A whole plant-based diet may improve ED by enhancing endothelial function.
  • Dietary interventions focusing on whole plant foods offer a potential strategy for managing ED and CVD risk.