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Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...

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Variational mode directed deep learning framework for breast lesion classification using ultrasound imaging.

Manali Saini1, Sara Hassanzadeh1, Bushira Musa2

  • 1Department of Radiology, Mayo Clinic College of Medicine and Science, Rochester, MN, 55905, USA.

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|April 24, 2025
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This study introduces a new AI framework for breast cancer detection using ultrasound. It improves accuracy and explainability in classifying lesions, offering a more efficient and reliable diagnostic tool.

Keywords:
Convolutional layersDeep learningMixed poolingUltrasoundVariational mode decomposition

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Oncology

Background:

  • Breast cancer is a leading cause of death in women, necessitating early detection.
  • Current deep learning methods for ultrasound-based breast lesion detection face challenges with explainability, segmentation, and computational cost.

Purpose of the Study:

  • To develop a novel ultrasound-based breast lesion classification framework.
  • To enhance the explainability and efficiency of deep learning models for breast cancer detection.

Main Methods:

  • Utilized two-dimensional variational mode decomposition (2D-VMD) to extract self-explanatory features.
  • Employed a convolutional neural network (CNN) with mixed pooling and attention mechanisms guided by 2D-VMD features.
  • Evaluated the framework on public and in-house breast ultrasound datasets without requiring lesion segmentation.

Main Results:

  • Achieved high classification accuracies: 98% and 93% on two public datasets, and 89% on an in-house dataset.
  • Demonstrated improved areas under the ROC (5%) and precision-recall (10%) curves.
  • Showcased significant computational efficiency with reduced floating-point operations compared to existing methods.

Conclusions:

  • The proposed 2D-VMD-guided CNN framework offers a highly accurate, explainable, and computationally efficient solution for breast lesion classification.
  • This approach overcomes limitations of existing methods by providing interpretable features and eliminating the need for segmentation.
  • The framework holds promise for improving early breast cancer detection and reducing mortality rates.