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KArAT (Knee Arthroplasty Activity Trial): Rationale and design features of a multicenter randomized controlled trial
Elena Losina1,2,3, Jamie E Collins1,2, Mahima Kumara1
1Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Osteoarthritis and Cartilage Open
|April 25, 2025
Summary
This study tested a behavioral intervention to increase physical activity after total knee arthroplasty (TKA). Health coaching and incentives show promise for improving post-surgery activity levels in knee osteoarthritis patients.
Area of Science:
- Orthopedics
- Behavioral Science
- Public Health
Background:
- Total knee arthroplasty (TKA) aims to relieve pain from severe knee osteoarthritis.
- Despite pain relief, physical activity (PA) often doesn't increase post-TKA.
- Behavioral interventions may enhance PA uptake after TKA.
Purpose of the Study:
- To evaluate a personalized behavioral intervention for increasing PA in TKA recipients.
- To establish the efficacy and sustainability of the intervention.
- To conduct a cost-effectiveness analysis of the intervention.
Main Methods:
- The Knee Arthroplasty Activity Trial (KArAT) is a three-arm, multi-center randomized controlled trial.
- Intervention arms: usual care, attention control (Fitbit), and health coaching with financial incentives.
- Primary outcome: proportion of participants achieving 150 minutes of moderate-to-vigorous PA weekly post-intervention.
Main Results:
- N/A - Study design and rationale outlined, results pending.
Conclusions:
- N/A - Study design and rationale outlined, conclusions pending.
