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Updated: May 21, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Inhaled Respiratory Therapy and Global Warming].
C Casanova-Martínez1, E Espino-Paisán1, L Buján-de-Gonzalo1
1Servizo de Xestión da Prestación Farmacéutica. Subdirección Xeral Farmacia. Dirección Xeral de Asistencia Sanitaria. SERGAS. Consellería de Sanidade. Santiago de Compostela. España. España.
Pressurized metered-dose inhalers (pMDIs) using hydrofluorocarbon propellants significantly contribute to global warming. This study assessed inhaler use and carbon footprint in Galicia, finding pMDIs responsible for nearly all emissions.
Area of Science:
- Environmental Science
- Public Health
- Pharmaceutical Sciences
Background:
- Hydrofluorocarbon (HFC) propellants in pressurized metered-dose inhalers (pMDIs) are potent greenhouse gases.
- The environmental impact of inhaler use, particularly pMDIs, is a growing concern in respiratory therapy.
- Understanding local patterns of inhaler use is crucial for developing targeted environmental strategies.
Purpose of the Study:
- To analyze the types and usage patterns of inhalers in the Galician population.
- To quantify the carbon footprint associated with inhaler use in Galicia.
- To evaluate the contribution of different inhaler types to overall greenhouse gas emissions.
Main Methods:
- An observational, descriptive, and retrospective study was conducted in Galicia in 2023.
- Data included patients receiving pharmaceutical care from the Galician Health Service (SERGAS) for respiratory conditions.
- Analysis focused on dispensed inhaler units and their associated carbon footprint.
Main Results:
- Over 1.7 million inhaler units were dispensed, generating a carbon footprint of 15,247,142 kg CO2eq.
- Pressurized metered-dose inhalers (pMDIs) constituted 43.17% of dispensed units but were responsible for 95.43% of the carbon footprint.
- Hydrofluoroalkane-134a (HFA-134a) was the most prevalent propellant in pMDIs, with 669,907 units dispensed.
Conclusions:
- Pressurized metered-dose inhalers (pMDIs) are the primary source of the carbon footprint from inhalers used in respiratory therapy.
- Strategies are being implemented by the Galician Health Service (SERGAS) to mitigate the environmental impact of pMDIs.
- Reducing reliance on HFC-propelled pMDIs is essential for lowering greenhouse gas emissions from respiratory treatments.
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