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Unveiling the Hidden Risks: Herbal Medicine-Induced Renal Damage - A Case Series Analysis
Ashok Bhat1, Rohan Desai1, Mahesha Vankalakunti2
1Department of Nephrology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Case Reports in Nephrology and Dialysis
|April 25, 2025
Summary
Herbal medications can cause kidney damage, with oxalate nephropathy being a key finding in this study. Early detection and stopping the herb improved patient outcomes.
Area of Science:
- Nephrology
- Toxicology
- Integrative Medicine
Background:
- Herbal remedies are widely used, particularly in rural India, for perceived holistic benefits.
- The potential for herbal medications to cause kidney damage is often underestimated.
- Cultural beliefs contribute to the popularity of herbal remedies.
Observation:
- A case series of 4 patients presented with diverse renal issues linked to herbal product consumption.
- Oxalate nephropathy was a significant finding in the observed cases.
- Clinical assessments and renal biopsies were used to understand the mechanisms of herbal nephrotoxicity.
Findings:
- Discontinuation of the implicated herbal medication was crucial for recovery.
- Therapeutic interventions, including corticosteroids, contributed to favorable patient outcomes.
- Herbal nephrotoxicity can manifest in various renal presentations.
Implications:
- Healthcare providers should consider herbal remedies as a potential cause of renal dysfunction.
- Inquiring about herbal medication use is essential for patients presenting with kidney failure.
- Increased awareness and research are needed to address herb-induced kidney injury and ensure patient safety.
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