Effective Skin Rejuvenation by a Novel Antioxidant Biostimulating Treatment

Area of Science:

• Dermatology and Aesthetic Medicine
• Biochemistry of Skin Aging
• Topical Therapeutics

Background:

• Facial skin aging results from intrinsic and extrinsic factors.
• Chemical peels are common noninvasive rejuvenation methods.
• Limited innovation exists in current chemical peel technology.

Purpose of the Study:

• To develop and evaluate a novel topical antioxidant biostimulating treatment (ABT).
• To utilize a chemical peel vehicle for delivering antioxidant biostimulating acidic phytocompounds (ABAP).
• To investigate the potential of ABAP for skin rejuvenation in the papillary dermis.

Main Methods:

• Ex vivo and in vivo studies were conducted.
• The ABT was tested on 32 female subjects (ages 38-60, Fitzpatrick skin types I-V).
• Efficacy and safety were assessed through clinical evaluation and photography.

Main Results:

• The ABT upregulated elastin and collagen by over 25% compared to controls.
• Significant improvements were observed in fine lines, wrinkles, tactile laxity, and overall appearance after three sessions.
• Clinical photography confirmed enhanced skin smoothness, radiance, and overall appearance.

Conclusions:

• The developed ABT with ABAP technology is effective for facial skin rejuvenation.
• The treatment demonstrated significant improvements in signs of skin aging.
• The ABT is safe for all skin tones.