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Using Invitation Letters to Increase HPV Vaccination Among Adult Women
Kelly Bunzeluk1, Laura Coulter1, Donna Turner1,2
1CancerCare Manitoba, Winnipeg, MB R3E 0V9, Canada.
Current Oncology (Toronto, Ont.)
|April 25, 2025
Summary
Sending invitation and reminder letters significantly increased human papillomavirus (HPV) vaccine uptake in eligible adult women. This low-cost intervention effectively boosted HPV vaccination coverage for those who missed school-based programs.
Area of Science:
- Public Health
- Immunization Programs
- Preventive Medicine
Background:
- Most HPV vaccinations in Manitoba occur through school-based programs.
- Adult women who miss school-based vaccination remain eligible for free HPV immunization.
- The study investigated methods to increase HPV vaccine uptake in this eligible adult population.
Purpose of the Study:
- To determine if invitation and reminder letters improve HPV vaccine uptake among adult women eligible for a publicly funded program.
- To assess the cost-effectiveness of mailed interventions for increasing vaccination coverage.
Main Methods:
- Randomized controlled trial with 3 groups (4650 women each).
- Intervention Group I received an invitation package.
- Intervention Group II received an invitation package followed by a reminder letter.
- Control group received no communication regarding HPV vaccination.
Main Results:
- Intervention Group II (invitation/reminder) had 4.0% HPV vaccine uptake.
- Intervention Group I (invitation only) had 2.5% HPV vaccine uptake.
- Compared to controls, invitation/reminders increased HPV vaccination likelihood by 4.9 times; invitations alone increased it by 3.0 times.
Conclusions:
- Mailed invitation and reminder letters are effective strategies for increasing HPV vaccination coverage in eligible adult women.
- This intervention offers a low-cost method to improve public health outcomes related to HPV immunization.
- Targeted communication can enhance participation in publicly funded vaccination programs.
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