Addressing semantic ambiguity in biotechnology: Proposals from the European research infrastructure IBISBA

Area of Science:

• Biotechnology and Advanced Manufacturing
• Scientific Terminology and Regulation

Background:

• Biotechnology, driven by biological discoveries, is poised to revolutionize advanced manufacturing using living organisms.
• Lack of clear, consensual definitions for key terms like biotechnology, biomanufacturing, synthetic biology, and engineering biology hinders regulatory clarity and public understanding.

Purpose of the Study:

• To examine the lexical complexity and definitional ambiguity within the biotechnology field.
• To argue for the harmonization of core terms to facilitate efficient policymaking and communication.

Main Methods:

• Analysis of the current state of terminology in biotechnology, biomanufacturing, synthetic biology, and engineering biology.
• Review of existing definitions and their interpretations in scientific and public discourse.

Main Results:

• Identified a longstanding debate and liberal interpretations surrounding the definition of biotechnology.
• Noted the absence of consensual definitions for biomanufacturing, synthetic biology, and engineering biology.
• Highlighted the emergence of new, potentially less scientifically grounded terms like precision fermentation and cellular agriculture.

Conclusions:

• Harmonizing definitions for biotechnology, biomanufacturing, engineering biology, and synthetic biology is vital for effective policymaking.
• Clear terminology is essential for efficient regulation, public engagement, and the responsible advancement of biotechnology.
• This discussion aims to support policymakers and science communicators in navigating the evolving landscape of biotechnology terminology.