Redesigning Clinical Decision Support for Retinopathy of Prematurity Screening After Alert Failure

Mikael Carl Gustav Guzman Karlsson1,2,3, Lauren M Hess1,4, Amy L Jeppesen1

  • 1Texas Children's Hospital, Houston, Texas, United States.

PubMed

Insights

An interruptive alert for retinopathy of prematurity (ROP) screening failed to identify at-risk infants during readmissions. Data analysis led to a switch to a more effective, non-interruptive surveillance dashboard.

Area of Science:

  • Pediatric ophthalmology
  • Clinical informatics
  • Healthcare quality improvement

Background:

  • Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in premature infants.
  • Current screening guidelines target infants with gestational age < 31 weeks or birthweight ≤ 1500g.
  • Timely ROP screening during post-birth readmissions presents significant logistical challenges.

Purpose of the Study:

  • To evaluate the performance of an interruptive clinical decision support (CDS) alert for ROP screening in readmitted premature infants.
  • To analyze how data from the alert's performance informed the transition to a non-interruptive surveillance dashboard.

Main Methods:

  • An interruptive alert was implemented for patients aged 1-365 days requiring ROP screening during hospital readmissions.
  • Alert metrics, user responses, patient demographics, and ophthalmology consultations were extracted from the hospital's data warehouse.
  • Statistical process control charts analyzed ophthalmology consultation rates before, during, and after alert implementation.

Main Results:

  • The alert triggered 3309 times across 2194 patient encounters.
  • Only 43% of encounters resulted in an "Accept and place order" response, with just 11% leading to an ophthalmology consult.
  • A significant portion of consultations (34%) occurred despite alternative user responses, indicating alert inefficiency.

Conclusions:

  • An analysis of the underperforming interruptive alert led to its deimplementation and replacement with a targeted, non-interruptive surveillance dashboard.
  • This transition highlights the critical need to align CDS tools with clinical workflows, data availability, and user decision-making processes.
  • Effective governance is essential for successful CDS implementation and optimization in healthcare settings.