Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

CRISPR

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...

What is Genetic Engineering?

What is Genetic Engineering?

Ethical Dilemmas I

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...

Probability Laws

Probability Laws

Ethics and Bioethics

Ethics and Bioethics

Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...

What is Population Genetics?

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Public perceptions and willingness to accept somatic gene therapy: A Belgian survey study.

Open research Europe·2026

Same author

Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review.

Open research Europe·2026

Same author

Disparities in access to gene therapy in the European Union: ethical and regulatory challenges.

Journal of law and the biosciences·2025

Same author

Vulnerability in research ethics: A systematic review of policy guidelines and documents.

PloS one·2025

Same author

REC review of deceptive studies: diversifying guidance for diverse review needs.

Medicine, health care, and philosophy·2025

Same author

Genomic findings with familial implications: agenda setting in light of mainstreaming.

Open research Europe·2025

Same journal

Tissue MicroRNAs in Arrhythmogenic Cardiomyopathy: A Systematic Review of Studies in Human Myocardium and Animal Models with Implications for Post-Mortem Molecular Diagnostics.

Genes·2026

Same journal

Genetic Variants and Dental Caries Susceptibility: An Umbrella Review and Multilevel Meta-Analysis.

Genes·2026

Same journal

Generative AI and Language Models in Human Genetics and Health: From Variant Interpretation to Clinical Decision Support.

Genes·2026

Same journal

Familial White-Sutton Syndrome Caused by a Pathogenic POGZ p.Arg508* Variant: Intrafamilial Variability from Childhood to Adulthood.

Genes·2026

Same journal

Genetic Influence on LDL-Cholesterol Levels: Role of Polygenic Risk Scores and Lp(a) Beyond Monogenic Hypercholesterolemia.

Genes·2026

Same journal

THBS1 as a Key Regulator of Myoblasts: Validation of Its Inhibitory Roles in Skeletal Muscle Development.

Genes·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 10, 2025

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Ethical and Practical Considerations in Implementing Population-Based Reproductive Genetic Carrier Screening.

Eva Van Steijvoort¹, Pascal Borry¹

¹Centre for Biomedical Ethics and Law, Department of Public Health and Primary Care, KU Leuven, Kapucijnenvoer 7 bus 7001, 3000 Leuven, Belgium.

|April 26, 2025

Summary

This summary is machine-generated.

Reproductive genetic carrier screening (RGCS) helps identify couples at risk for genetic conditions, supporting informed reproductive choices. This review examines RGCS

Keywords:

ethics genetic carrier screening implementation informed decision-making reproduction

More Related Videos

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

Related Experiment Videos

Last Updated: May 10, 2025

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

Area of Science:

Genetics
Reproductive Medicine
Public Health

Background:

Reproductive genetic carrier screening (RGCS) identifies couples at risk for autosomal recessive or X-linked genetic conditions.
Historically, screening targeted high-risk groups to reduce specific genetic disorder prevalence.
Recent shifts favor broader, population-based RGCS to enhance reproductive autonomy and address healthcare inequities.

Purpose of the Study:

To explore the complexities of implementing reproductive genetic carrier screening.
To emphasize the significance of informed decision-making in RGCS.
To analyze the societal challenges and ethical considerations of widespread RGCS.

Main Methods:

Literature review of reproductive genetic carrier screening initiatives.
Analysis of the evolution of RGCS from targeted to population-based approaches.
Examination of ethical considerations and societal implications of RGCS.

Main Results:

RGCS supports informed reproductive decision-making through early detection.
Broader RGCS aims to increase reproductive autonomy and equity.
Population-based RGCS raises ethical questions regarding individual autonomy vs. public health goals and potential negative effects.

Conclusions:

RGCS implementation involves balancing individual autonomy with public health objectives.
Informed decision-making is crucial for ethical and effective RGCS.
Potential uses of RGCS data for other health initiatives require careful ethical consideration.