PROGRESS (Patient-Reported Outcomes in Genital Reconstructive Surgeries): A Validated Patient-Reported Outcome...

Area of Science:

• Medical and Health Sciences
• Surgical Outcomes Research
• Patient-Reported Outcome Measures

Background:

• Patient-reported outcome measures (PROMs) are crucial for evaluating surgical success.
• Standardized tools are needed to assess outcomes in feminizing genital reconstructive surgery (fGRS).

Purpose of the Study:

• To validate the Patient Reported Outcomes in Genital REconstructive SurgerieS (PROGRESS) questionnaire.
• To assess its reliability and suitability for patients undergoing fGRS.

Main Methods:

• The PROGRESS questionnaire assessed urinary, sexual, cosmetic, bowel function, and general health.
• 117 patients completed pre- and post-operative questionnaires (52 weeks).
• Internal consistency (Cronbach's alpha) was used to determine reliability.

Main Results:

• Significant improvements were observed in overall scores post-fGRS (median change -35.8%, p < 0.001).
• High reliability (Cronbach's alpha) was found for urinary, sexual, cosmetic, and general health domains.
• Bowel function domain showed lower reliability.

Conclusions:

• The PROGRESS questionnaire is a validated and reliable tool for assessing outcomes after fGRS.
• It provides a standardized method for evaluating functional improvements in clinical practice.