Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

24
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
24
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.0K
Mitochondria01:37

Mitochondria

8.9K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
8.9K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.6K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamin D as a Lifespan Neuroimmune Signal in Psychiatry: From Developmental Risk to Precision Nutrition.

Nutrients·2026
Same author

Geroprotective Potential of <i>Centella asiatica</i>: Modulation of Cellular Aging.

Nutrients·2026
Same author

Clonal Hematopoiesis (CHIP) in Pulmonary Embolism and CTEPH: Evidence, Mechanisms, and Risk Stratification.

International journal of molecular sciences·2026
Same author

The Role of Probiotics and Their Postbiotic Metabolites in Post-COVID-19 Syndrome.

Molecules (Basel, Switzerland)·2025
Same author

The Endocannabinoid System in the Development and Treatment of Obesity: Searching for New Ideas.

International journal of molecular sciences·2025
Same author

Subchronic Treatment with CBZ Transiently Attenuates Its Anticonvulsant Activity in the Maximal Electroshock-Induced Seizure Test in Mice.

International journal of molecular sciences·2025
Same journal

Correction: Pramesthi et al. Evaluating the Impact of Indonesia's National School Feeding Program (ProGAS) on Children's Nutrition and Learning Environment: A Mixed-Methods Approach. <i>Nutrients</i> 2025, <i>17</i>, 3575.

Nutrients·2026
Same journal

Correction: Huang et al. Correlation Study Between Dietary Behaviors, Lifestyle, and Psychological Problems in Chinese Children Aged 3-7. <i>Nutrients</i> 2025, <i>17</i>, 176.

Nutrients·2026
Same journal

Association of Dietary Animal and Plant Protein Composition with All-Cause Mortality: 24-Year Population-Based Cohort Study.

Nutrients·2026
Same journal

Phytochemistry, Bioavailability, and Molecular Mechanisms Underlying Multitarget Anticancer Activity of <i>Aloe vera</i>.

Nutrients·2026
Same journal

A Comparison of the Interstitial and Blood Glucose Responses Following Consumption of Different Carbohydrate-Containing Beverages in Humans: A Randomised Controlled Trial.

Nutrients·2026
Same journal

Across Kingdoms: The Bacteriome, Mycobiome, and Virome in Autoimmune Diseases: Mechanistic Insights, Therapeutic Perspectives, and the Emerging Role of COVID-19.

Nutrients·2026
See all related articles

Related Experiment Video

Updated: May 10, 2025

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
10:33

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells

Published on: November 18, 2022

1.2K

Astragalus Membranaceus-Can It Delay Cellular Aging?

Kinga K Borowicz1, Monika E Jach2

  • 1Independent Experimental Neuropathophysiology Unit, Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 8b Street, 20-090 Lublin, Poland.

Nutrients
|April 26, 2025
PubMed
Summary
This summary is machine-generated.

Astragalus membranaceus, a traditional Chinese herb, offers potent anti-aging benefits by protecting cells from damage. Its root extract supports skin health and enhances the function of multiple body systems.

Keywords:
Astragalus membranaceusanti-aging effectscellular senescenceskin agingsystemic aging

More Related Videos

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

33.0K
SA-&#946;-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
07:39

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs

Published on: June 28, 2019

23.6K

Related Experiment Videos

Last Updated: May 10, 2025

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
10:33

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells

Published on: November 18, 2022

1.2K
Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

33.0K
SA-&#946;-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
07:39

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs

Published on: June 28, 2019

23.6K

Area of Science:

  • Herbal Medicine
  • Pharmacology
  • Gerontology

Background:

  • Astragalus membranaceus is a revered herb in Traditional Chinese Medicine, known for its adaptogenic qualities.
  • The plant's root is rich in bioactive compounds like polysaccharides, flavonoids, and saponins.
  • It is traditionally recognized for its health-promoting and longevity-enhancing properties.

Purpose of the Study:

  • To review the composition of Astragalus membranaceus.
  • To elucidate the beneficial effects of its root extract and active compounds on overall health.
  • To focus on the anti-aging impacts of Astragalus membranaceus on the skin.

Main Methods:

  • Literature review of studies on Astragalus membranaceus.
  • Analysis of its chemical constituents.
  • Examination of research on its physiological effects, particularly on skin aging and systemic functions.

Main Results:

  • Astragalus membranaceus contains polysaccharides, flavonoids, and saponins with diverse biological activities.
  • The herb demonstrates antioxidant, immunomodulatory, anti-inflammatory, and regenerative properties.
  • Evidence suggests Astragalus membranaceus can prevent cellular aging, maintain skin condition, and support multiple organ systems.

Conclusions:

  • Astragalus membranaceus possesses significant anti-aging potential due to its rich composition and multifaceted actions.
  • Its root extract offers protective benefits against cellular senescence and supports systemic health.
  • Further research into Astragalus membranaceus can validate its therapeutic applications in anti-aging and overall wellness.