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Mid-line epileptiform activity in adult electroencephalograms
Clinical EEG (Electroencephalography)
|January 1, 1985
Summary
Epileptiform discharges in the C-Z area were found in 0.9% of adults. These EEG findings correlated with dementia and cerebral atrophy, suggesting structural changes cause midline epileptiform activity.
Area of Science:
- Neurology
- Neurophysiology
- Clinical Electrophysiology
Background:
- Epileptiform discharges are abnormal EEG findings.
- Midline epileptiform activity is rare in adults.
Purpose of the Study:
- To investigate the prevalence and characteristics of epileptiform discharges in the C-Z area in adults.
- To explore the association between these EEG findings and cognitive status or brain structure.
Main Methods:
- Retrospective analysis of 1000 adult EEG recordings.
- Identification of epileptiform discharges in the C-Z area.
- Clinical assessment for dementia and CT scans for cerebral atrophy.
Main Results:
- Nine cases (0.9%) showed C-Z epileptiform discharges: 5 with spike-wave (0.5%), 4 with Mu-like rhythms (0.4%).
- All cases exhibited varying degrees of dementia.
- CT scans revealed mild to moderate cerebral atrophy and ventricular enlargement.
Conclusions:
- Diffuse cortical and subcortical structural alterations may underlie midline epileptiform activity in adults.
- This activity may be a marker for underlying brain pathology in adults.