Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The economic burden of MASH: comparison of healthcare resource utilization and costs in patients with probable MASH, without MASH, and with diagnosed MASH.

Expert review of pharmacoeconomics & outcomes research·2026
Same author

Accuracy of the FIB-4 and LiverRisk score for use in primary risk assessment for liver fibrosis, and variation by age.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same author

Refining HEPAmet for Treatment Eligibility in Metabolic Dysfunction-Associated Steatotic Liver Disease: External Validation and Guardrail to Exclude Cirrhosis, Limit Early Disease.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

Comparative efficacy of phase 2-3 therapies for non-cirrhotic metabolic dysfunction-associated steatohepatitis: An updated network meta-analysis.

Med (New York, N.Y.)·2026
Same author

Clinical Outcomes and Non-Invasive Testing in Metabolic Dysfunction-Associated Steatohepatitis With Cirrhosis: A Systematic Review.

Liver international : official journal of the International Association for the Study of the Liver·2026
Same author

Therapeutic targets for metabolic dysfunction-associated steatohepatitis: a personalized approach to disease management.

Nature reviews. Gastroenterology & hepatology·2026

Related Experiment Video

Updated: May 12, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

7.7K

Liver Transplantation: Changing Indications and Changing Candidates.

Michael Charlton1, Mary E Rinella1

  • 1Center for Liver Diseases, The University of Chicago, Chicago, IL, USA.

Clinics in Liver Disease
|April 26, 2025
PubMed
Summary

Liver transplant indications are shifting, with fewer hepatitis C cases and more metabolic and alcohol-related liver disease. Current organ allocation policies may not equitably serve all patients needing transplants.

Keywords:
DonorsIndicationsLiver transplantationRecipients

More Related Videos

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.3K
Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
09:23

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

Published on: September 22, 2023

2.5K

Related Experiment Videos

Last Updated: May 12, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

7.7K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.3K
Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
09:23

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

Published on: September 22, 2023

2.5K

Area of Science:

  • Hepatology
  • Transplantation Medicine
  • Public Health

Background:

  • Liver transplantation numbers and donor organs have doubled in two decades.
  • Geographic disparities in access to liver transplantation persist.
  • Therapies for hepatitis C virus (HCV) have decreased HCV-related cirrhosis as a transplant indication.

Purpose of the Study:

  • To analyze the evolving indications for liver transplantation.
  • To assess the impact of changing disease prevalence on transplant allocation.
  • To evaluate the equity of MELD score-based allocation across different liver disease etiologies.

Main Methods:

  • Retrospective analysis of liver transplant data.
  • Examination of trends in transplant indications over 20 years.
  • Comparison of MELD score distribution across various liver disease types.

Main Results:

  • Significant increase in liver transplants for metabolic dysfunction-associated steatohepatitis and alcohol-related liver disease.
  • Decline in liver transplantation for hepatitis C virus (HCV)-related cirrhosis.
  • MELD score-based allocation does not equally benefit all indications for liver transplantation.

Conclusions:

  • Liver transplant indications are rapidly evolving.
  • Current organ allocation policies may require adjustments to address changing disease patterns and ensure equitable access.
  • Further research is needed to optimize allocation systems for diverse patient populations.