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Stereotactic Radiosurgery for Gynecologic Cancer
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Same-day mask-based gamma-knife stereotactic radiosurgery: workflow analysis and impact.

Mark Mizrachi1, Iñigo L Sistiaga1, Benjamin Hartley1

  • 1Department of Neurosurgery, United States; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, United States.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|April 27, 2025
PubMed
Summary

Same-day mask fabrication and stereotactic radiosurgery (SRS) is feasible and safe. While same-day SRS treatments show more pauses, they do not significantly prolong overall treatment time, enhancing patient convenience.

Keywords:
Gamma knifeMask fabricationSRSStereotactic radiosurgery

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Medical Physics

Background:

  • Stereotactic radiosurgery (SRS) increasingly utilizes mask immobilization for patient comfort and hypofractionation.
  • Traditional mask-based SRS requires separate days for fabrication and treatment, impacting patient visits.
  • This study investigates the feasibility of same-day mask fabrication and SRS treatment.

Purpose of the Study:

  • To evaluate the safety and efficiency of performing mask fabrication and SRS on the same day.
  • To compare treatment parameters between same-day and different-day SRS procedures.
  • To assess the impact on treatment time, pauses, and alarms.

Main Methods:

  • Retrospective review of 100 patients undergoing SRS from September 2020 to June 2021.
  • Analysis of Leksell Gamma Knife (LGK) console data and operator reports.
  • Comparison of treatment time, pauses, alarms, and pause durations between same-day and different-day groups.

Main Results:

  • 52 patients had same-day fabrication and treatment; 48 had treatment on a subsequent day.
  • Same-day group experienced more frequent and longer pauses.
  • No significant differences were observed in predicted vs. actual treatment times or number of alarms.

Conclusions:

  • Mask-based SRS can be safely and efficiently performed on the same day as fabrication.
  • Increased pauses in same-day treatments do not lead to significant delays.
  • Same-day SRS may improve patient satisfaction by reducing facility visits.