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Updated: May 10, 2025

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
[Pathogenesis of fibrosis development in ovarian endometriosis]
O I Patsap1,2, O V Bratchikova3, A V Babkina4
1Federal Center of Brain Research and Neurotechnologies, Moscow, Russia.
Abstract:
Endometriosis-associated fibrosis is a complex phenomenon, and the underlying mechanisms are still not fully understood. Fibrosis is invariably present in all forms of the disease and contributes to the classic endometriosis-associated symptoms such as chronic pelvic pain and infertility. The purpose of this literature review was to study the role of various cell populations, biological mechanisms and signaling pathways in inducing fibrogenesis of endometriosis lesions. PubMed and MEDLINE searched for studies published in English over the past 5 years that studied fibrosis in ovarian endometriosis.
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