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Published on: February 14, 2022
Bridge to Heart Transplantation Using the Impella Device in a Pediatric Patient
Hüseyin Sicim1, Mohamad Alaeddine1, Daniel A Velez1
1Department of Congenital Cardiac Surgery, Phoenix Children's Hospital, Phoenix, AZ, USA.
Insights
Mechanical circulatory support is limited for children with acute heart failure. A 12-year-old patient with severe left ventricular dysfunction was successfully bridged to heart transplant using an Impella 5.5 device.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Medical Device Technology
Background:
- Limited mechanical circulatory support options exist for pediatric acute heart failure.
- Managing pediatric patients with heart failure presents unique size and support challenges.
- Left ventricular assist devices are sometimes required for pediatric extracorporeal support.
Purpose of the Study:
- To describe the successful use of a specific mechanical circulatory support device in a pediatric patient with acute heart failure.
- To demonstrate a viable bridging strategy to heart transplantation for pediatric patients with severe left ventricular dysfunction.
Main Methods:
- Implantation of an Impella 5.5 device in a 12-year-old patient with severe left ventricular dysfunction.
- Anterograde insertion of the device via a 10-mm Hemashield graft to the right innominate artery.
- Utilizing the device as a bridge to heart transplantation after failure of medical therapy.
Main Results:
- Successful stabilization of the pediatric patient with acute heart failure.
- The Impella 5.5 device effectively supported the patient's circulation.
- The patient was successfully bridged to a subsequent heart transplant.
Conclusions:
- The Impella 5.5 device can be a safe and effective mechanical circulatory support option for select pediatric patients with acute heart failure.
- This case highlights a successful strategy for bridging pediatric patients to heart transplantation when medical therapy fails.
- Advanced mechanical circulatory support devices offer promising solutions for complex pediatric cardiac conditions.
Abstract:
Mechanical circulatory support options for pediatric patients with acute heart failure are limited. These patients can be challenging to manage depending on their size and the type of extracorporeal support required including the need for a left ventricular assist device. We report the case of a 12-year-old child with severely depressed left ventricular function who did not respond to medical therapy. We successfully stabilized the patient and bridged him to a successful heart transplant by implanting an Impella 5.5 device via a 10-mm Hemashield graft to the right innominate artery.

