[Plasma cell leukemia: new diagnostic and therapeutic perspectives (about five cases)]

Plasma cell leukemia (PCL) is a rare lymphoproliferative disorder characterized by clonal proliferation of plasma cells in the bone marrow and peripheral blood. In 2021, the International Myeloma Working Group (IMWG) redefined LCP as the presence of 5% or more circulating plasma cells in patients otherwise diagnosed with multiple myeloma. In this work, we report five cases of PCL collected in the hematology laboratory of the Mohammed VI University Hospital in Oujda. The interest of this work is to elucidate the importance of hematological cytology in diagnostic guidance as well as therapeutic innovation concerning this rare pathology.