[Study of cerebral blood flow by the xenon-133 method in 10 schizophrenic adolescents]

Regional cerebral blood flow (r CBF) was compared in ten adolescents with hebephrenia who were never treated with neuroleptics and ten normal controls using the Xenon 133 inhalation method. There were no differences in mean hemispheric blood flow. The main difference was the loss of the "hyperfrontal pattern" in the schizophrenics: the prefrontal values were only 0.7% greater than the blood flow in the rest of the hemisphere, compared with 14.6% in the controls.