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Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
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Catheter-Related Bladder Discomfort: Insights Into Pathophysiology, Clinical Impact, and Management
Titos Markopoulos1, Stamatios Katsimperis1, Lazaros Lazarou1
1Second Department of Urology, National and Kapodistrian University of Athens, Sismanogleio General Hospital, Athens, GRC.
Cureus
|April 28, 2025
Summary
Catheter-related bladder discomfort (CRBD) causes significant postoperative pain and urinary urgency. This review covers CRBD management, focusing on bladder spasms after transurethral surgeries like TURBT and TURP.
Area of Science:
- Urology
- Anesthesiology
- Postoperative Care
Background:
- Catheter-related bladder discomfort (CRBD) is a common issue after transurethral surgeries.
- CRBD presents as suprapubic pain, urgency, and bladder spasms, often linked to muscarinic receptor activation.
Purpose of the Study:
- To provide a comprehensive review of CRBD.
- To specifically analyze bladder spasms in patients undergoing transurethral resection of bladder tumors (TURBT) or transurethral resection of the prostate (TURP).
Main Methods:
- This study is a narrative review.
- It synthesizes existing literature on CRBD pathophysiology, clinical impact, and management strategies.
Main Results:
- CRBD significantly impairs patient recovery and quality of life post-surgery.
- Management strategies include pharmacological options (antimuscarinics, nerve blocks) and non-pharmacological approaches.
Conclusions:
- Effective management of CRBD and associated bladder spasms is crucial for improving patient outcomes after transurethral procedures.
- A multimodal approach combining pharmacological and non-pharmacological interventions is recommended.
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