Design framework to develop sustainable innovations for addressing One Health challenges

Area of Science:

• Global Health
• Interdisciplinary Studies
• Public Health

Background:

• Global health issues demand integrated, cross-boundary solutions.
• One Health (OH) provides a holistic framework for human, animal, and environmental health.
• Antimicrobial Resistance (AMR) exemplifies a complex, cross-sectoral OH challenge requiring coordinated action.

Purpose of the Study:

• To address the limitations of current frameworks for OH challenges and AMR.
• To propose a structured, user-centered theoretical framework for developing sustainable OH interventions.
• To bridge the gap in comprehensive, integrated approaches aligned with OH principles.

Main Methods:

• Development of the HEARTf of OHC (Holistic Engagement and Adaptive Responses Theoretical framework of One Health challenges).
• Integration of knowledge from social sciences, computer science, industrial design, pedagogy, and health sciences.
• Review of existing AMR frameworks to identify limitations and the need for transdisciplinarity.

Main Results:

• The HEARTf of OHC offers a user-centered design approach for sustainable OH interventions.
• The framework integrates diverse knowledge domains to create context-specific solutions.
• AMR is used as a case study to demonstrate the framework's application in intervention design and evaluation.

Conclusions:

• The HEARTf of OHC provides a generalizable model for designing, implementing, and evaluating OH interventions.
• Emphasizes user-centered design, transdisciplinarity, and continuous evaluation for improved outcomes.
• Addresses the need for structured theoretical approaches to enhance the sustainability and innovation of OH solutions.