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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: May 10, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Case Image: Cutaneous Leiomyoma.

Sunil Jaiswal1, Shraddha Uprety1, Pratichya Thapa1

  • 1Department of Dermatology Chitwan Medical College Bharatpur Nepal.

Clinical Case Reports
|April 28, 2025
PubMed
Summary
This summary is machine-generated.

Cutaneous leiomyomas are rare benign smooth muscle tumors. Multiple lesions warrant screening for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC).

Keywords:
clustered papulescutaneous leiomyomahistopathological diagnosissmooth muscle

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Area of Science:

  • Oncology
  • Dermatology
  • Genetics

Background:

  • Cutaneous leiomyomas are uncommon benign neoplasms originating from smooth muscle tissue.
  • These tumors typically manifest as painful dermal nodules but can also be asymptomatic.

Purpose of the Study:

  • To highlight the diagnostic significance of histopathology for cutaneous leiomyomas.
  • To emphasize the importance of screening for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) in specific clinical contexts.

Main Methods:

  • Review of clinical presentations and histopathological findings of cutaneous leiomyomas.
  • Analysis of diagnostic criteria and recommended follow-up protocols.

Main Results:

  • Histopathology is confirmed as the definitive diagnostic method for cutaneous leiomyomas.
  • The presence of multiple cutaneous leiomyomas is identified as a key indicator for further genetic screening.

Conclusions:

  • Accurate diagnosis of cutaneous leiomyomas relies on histopathological examination.
  • Systematic screening for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) is crucial in patients with multiple cutaneous leiomyomas to detect this associated hereditary cancer syndrome.