Related Experiment Video
Updated: May 10, 2025
16:08
Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition
Published on: February 1, 2012
16.1K
Correlation Between COVID-19 Recovery, Executive Function Decline, and Emotional State
Daniela María Velásquez Cabrera1, Jose Maria De la Roca-Chiapas2, Martha Alicia Hernández-González3
1Health Sciences Division, University of Guanajuato, Guanajuato, Mexico.
Psychology Research and Behavior Management
|April 28, 2025
Summary
Long COVID may cause executive function decline, particularly in stimulus inhibition, over time. Depression is linked to cognitive impairment, necessitating cognitive rehabilitation and psychological support for patients recovering from COVID-19.
Area of Science:
- Neuroscience
- Psychiatry
- Infectious Diseases
Background:
- Persistent symptoms after coronavirus disease 2019 (COVID-19) infection are common.
- Executive functions and emotional state are frequently affected in post-COVID-19 patients.
Purpose of the Study:
- To investigate the relationship between time since COVID-19 recovery and executive function alterations.
- To evaluate the emotional state of individuals post-COVID-19.
Main Methods:
- 67 patients aged 18-50 with prior COVID-19 (mild to severe) were assessed.
- Neuropsychological tests (BANFE-3, MMSE) and psychiatric interviews (MINI) were utilized.
- Spearman's correlation and logistic regression analyzed data, with p<0.05 significance.
Main Results:
- 19.4% of participants showed executive function deficits, with mental flexibility most impacted.
- A negative correlation between orbitofrontal area scores and time since recovery was observed, indicating potential deterioration in stimulus inhibition.
- 67.2% experienced emotional alterations, with anxiety and depression being prevalent. Depression was associated with higher likelihood of executive function impairment.
Conclusions:
- COVID-19 can lead to executive function deficits, possibly due to progressive orbitofrontal damage and impaired stimulus inhibition.
- Depression is a potential indicator of cognitive impairment in COVID-19 survivors.
- Cognitive rehabilitation and psychological support are crucial for post-COVID-19 recovery.
Related Concept Videos
01:03Long-term Depression
2.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
2.4K
01:27Depressive Disorders: Etiology
17
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
17
01:30Negative and Cognitive Symptoms of Schizophrenia
29
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
29
01:30Stress and Mental Health
47
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
47
01:18Depression: Overview
188
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
188
01:20Psychological Responses to Stress
21
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
21