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Published on: September 17, 2014
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Liquid Embolic Volume Correlates With Improved Chronic Subdural Hematoma Resolution After Middle Meningeal Artery
Alice Hung1, Wuyang Yang2, Kathleen Ran1
1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore , Maryland , USA.
Operative Neurosurgery (Hagerstown, Md.)
|April 28, 2025
Summary
The volume of embolic material used in middle meningeal artery (MMA) embolization significantly impacts chronic subdural hematoma (cSDH) resolution. The number of embolized MMA branches did not affect outcomes, suggesting volume is key for successful cSDH treatment.
Area of Science:
- Neurosurgery
- Interventional Radiology
- Vascular Neurology
Background:
- Middle meningeal artery (MMA) embolization is effective for chronic subdural hematomas (cSDH).
- The impact of distal embolic penetration on cSDH resolution is debated.
- This study investigates technical factors influencing cSDH clearance after MMA embolization.
Purpose of the Study:
- To evaluate the effect of embolized MMA branches and embolic material volume on cSDH radiographic resolution.
- To compare outcomes between patients with single versus multiple distal MMA branch embolization.
Main Methods:
- Retrospective review of 131 MMA embolizations for cSDH treatment.
- Comparison of baseline characteristics and technical parameters (branches embolized, embolic volume) between resolved and persistent cSDH.
- Univariate statistical analysis to determine significant factors.
Main Results:
- 70 out of 131 (53.4%) cSDH cases achieved complete radiographic resolution.
- Older age, kidney disease, and larger subdural size were associated with persistent cSDH.
- Embolic material volume, but not the number of embolized MMA branches, significantly correlated with cSDH resolution (P = .04).
Conclusions:
- Embolic material volume is a significant predictor of radiographic cSDH resolution post-MMA embolization.
- The number of embolized MMA branches does not influence cSDH resolution rates.
- Future procedural optimization should consider embolic volume and targeted MMA branch selection to improve cSDH clearance.

