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Published on: October 14, 2022
Craniovertebral lipoma associated with hydrocephalus: report of two cases
Kirill Sysoev1, Arina Kulaeva2, Dimitrios Tsiptsios3
1Division of Pediatric Neurosurgery, Almazov National Medical Research Centre, St. Petersburg, Russian Federation. sysoev.rnsi@mail.ru.
Insights
Craniovertebral lipomas in children, though rare, can cause hydrocephalus. Surgical removal of these tumors may still necessitate shunts due to persistent ventriculomegaly, with unclear underlying causes.
Area of Science:
- Pediatric Neurosurgery
- Neurology
- Developmental Biology
Background:
- Craniovertebral lipomas are rare congenital tumors.
- Hydrocephalus is an uncommon but serious complication of craniovertebral lipomas.
- The exact pathogenesis of hydrocephalus in these cases remains poorly understood.
Purpose of the Study:
- To report two pediatric cases of craniovertebral lipomas associated with hydrocephalus.
- To discuss the management and outcomes of these rare conditions.
- To highlight the challenges in understanding hydrocephalus development in this context.
Main Methods:
- Case presentation of two pediatric patients with craniovertebral lipomas and hydrocephalus.
- Surgical resection of the craniovertebral lipomas.
- Management of hydrocephalus, including ventriculoperitoneal shunt placement.
- Long-term clinical follow-up.
Main Results:
- Both patients presented with craniovertebral lipomas and hydrocephalus.
- Surgical lipoma resection did not resolve the hydrocephalus in either case.
- Both patients required ventriculoperitoneal shunts for exaggerated ventriculomegaly.
- Symptoms of increased intracranial pressure regressed, and patients remained stable long-term.
Conclusions:
- Craniovertebral lipomas can lead to complex hydrocephalus requiring surgical intervention beyond tumor removal.
- The etiology of progressive hydrocephalus post-lipoma resection in children is not fully elucidated.
- Further research is needed to understand the pathogenesis of hydrocephalus in craniovertebral lipomas.
Abstract:
Craniovertebral lipomas in children are rare, especially in association with hydrocephalus. We present two cases of craniovertebral lipomas, accompanied by hydrocephalus. Despite eliminating cerebrospinal fluid pathway occlusion as a result of lipoma resection, both patients were complicated by exaggerated ventriculomegaly requiring ventriculoperitoneal shunt placement. Eventually, both children were discharged home after regression of symptoms of increased intracranial pressure and remained stable during long-term follow-up. However, the pathogenesis of expanding hydrocephalus in such cases is yet unclear.
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